Anti-MEK4 (phospho S80) antibody [EP1075Y] (ab52958)

Overview

• Product nameAnti-MEK4 (phospho S80) antibody [EP1075Y]
  See all MEK4 primary antibodies
• Description
  Rabbit monoclonal [EP1075Y] to MEK4 (phospho S80)
• Tested applicationsSuitable for: IHC-P, WB, IPmore details
  Unsuitable for: Flow Cyt or ICC
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  A synthetic peptide corresponding to residues near the N-terminal of human MKK4

• Positive control
  • 3T3 cell lysates (untreated or treated with PDGF) and human muscle tissue.
• General notes

  Produced using Abcam’s RabMAb^® technology. RabMAb^® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

  A trial size is available to purchase for this antibody.

  Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• PurityTissue culture supernatant
• ClonalityMonoclonal
• Clone numberEP1075Y
• IsotypeIgG
• Research areas
  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • MAPK Pathway

Applications

Target

• FunctionDual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
• Tissue specificityAbundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
• Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
  Contains 1 protein kinase domain.
• Post-translational
  modificationsActivated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.

• Target information above from: UniProt accession P45985 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 6416 Human
  • Entrez Gene: 26398 Mouse
  • Omim: 601335 Human
  • SwissProt: P45985 Human
  • SwissProt: P47809 Mouse
  • Unigene: 514681 Human
  • Unigene: 412922 Mouse
• Alternative names
  • c Jun N terminal kinase kinase 1 antibody
  • C-JUN N-terminal kinase kinase 1 antibody
  • Dual specificity mitogen activated protein kinase kinase 4 antibody

  • Dual specificity mitogen-activated protein kinase kinase 4 antibody
  • JNK Activated Kinase 1 antibody
  • JNK activating kinase 1 antibody
  • JNK-activating kinase 1 antibody
  • JNKK antibody
  • JNKK1 antibody
  • MAP kinase kinase 4 antibody
  • Map2k4 antibody
  • MAPK ERK kinase 4 antibody
  • MAPK/ERK kinase 4 antibody
  • MAPKK 4 antibody
  • MAPKK4 antibody
  • MEK 4 antibody
  • MEK4 antibody
  • Mitogen activated protein kinase kinase 4 antibody
  • MKK 4 antibody
  • MKK4 antibody
  • MP2K4_HUMAN antibody
  • PRKMK4 antibody
  • SAPK ERK kinase 1 antibody
  • SAPK/ERK kinase 1 antibody
  • SAPKK 1 antibody
  • SAPKK1 antibody
  • SEK1 antibody
  • SERK1 antibody
  • SKK1 antibody
  • Stress activated protein kinase kinase 1 antibody

  see all