• Product nameAnti-MEK5 antibody
    See all MEK5 primary antibodies
  • Description
    Rabbit polyclonal to MEK5
  • Specificityab70611 does not cross react with phosphorylated MEK5.
  • Tested applicationsSuitable for: WB, IP, ELISA, Dot Blotmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Chicken, Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic non-phosphopeptide (Human) surrounding the epitope SIAKT (amino acids 311 -315) from MEK5.

  • Positive control
    • Whole cell lysates derived from mouse liver.


Associated products


Our Abpromise guarantee covers the use of ab70611 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 1 µg/ml. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).
IP Use a concentration of 2 - 5 µg/ml.
ELISA Use a concentration of 0.01 - 0.1 µg/ml.
Dot Blot 1/1000.


  • FunctionActs as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
  • Tissue specificityExpressed in many adult tissues. Abundant in heart and skeletal muscle.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 OPR domain.
    Contains 1 protein kinase domain.
  • DomainBinds MAP3K2/MAP3K3 and MAPK7 via non-overlapping residues of the OPR domain. This domain also mediates interactions with SQSTM1 and PARD6A.
  • Post-translational
    Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.
    Yersinia yopJ may acetylate Ser/Thr residues, preventing phosphorylation and activation, thus blocking the MAPK signaling pathway.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dual specificity mitogen activated protein kinase kinase 5 antibody
    • Dual specificity mitogen-activated protein kinase kinase 5 antibody
    • EC antibody
    • HsT17454 antibody
    • MAP kinase kinase 5 antibody
    • MAP kinase kinase MEK5b antibody
    • MAP2K5 antibody
    • MAPK/ERK kinase 5 antibody
    • MAPKK 5 antibody
    • MAPKK5 antibody
    • MEK 5 antibody
    • mitogen-activated protein kinase kinase 5 antibody
    • MKK5 antibody
    • MP2K5_HUMAN antibody
    • PRKMK5 antibody
    • Protein kinase, mitogen-activated, kinase 5 antibody
    • SAPKK5 antibody
    • SKK5 antibody
    see all

Anti-MEK5 antibody images

  • All lanes : Anti-MEK5 antibody (ab70611) at 1/1000 dilution

    Lane 1 : Whole cell lysates derived from mouse liver
    Lane 2 : Negative control

    Predicted band size : 49 kDa
    Observed band size : 49 kDa
  • 1 µg peptide was spotted onto NC membrane and blotted using ab70608 (Lane 1) or ab70611 (Lane 2) at 1/1000 dilution. A:MEK5 (pS311/pT315), B: MEK5 (Non-phosphorylated), C: Non-related phosphospecific PP.

References for Anti-MEK5 antibody (ab70611)

ab70611 has not yet been referenced specifically in any publications.

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