Overview

  • Product nameAnti-MEK6 antibody
    See all MEK6 primary antibodies
  • Description
    Rabbit polyclonal to MEK6
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length human MEK6 protein (His tagged) purified from E.coli

  • Positive control
    • HeLa, NIH3T3 and C6 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab71938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/2000. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).

Target

  • FunctionCatalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.
  • Tissue specificityIsoform 2 is only expressed in skeletal muscle. Isoform 1 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
  • Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Weakly autophosphorylated.
    Acetylation of Ser-207 and Thr-211 by Yersinia yopJ prevents phosphorylation and activation, thus blocking the MAPK signaling pathway.
  • Information by UniProt
  • Database links
  • FormIt localizes to nucleus, cytoplasm and cytoskeleton. Note: Binds to microtubules.
  • Alternative names
    • Dual specificity mitogen activated protein kinase kinase 6 antibody
    • Dual specificity mitogen-activated protein kinase kinase 6 antibody
    • MAP kinase kinase 6 antibody
    • MAP2K6 antibody
    • MAPK/ERK kinase 6 antibody
    • MAPKK 6 antibody
    • MAPKK6 antibody
    • MEK 6 antibody
    • MEK6 antibody
    • Mitogen Activated Protein Kinase Kinase 6 antibody
    • MKK 6 antibody
    • MKK6 antibody
    • MP2K6_HUMAN antibody
    • PRKMK6 antibody
    • Protein kinase mitogen activated kinase 6 antibody
    • protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) antibody
    • SAPK kinase 3 antibody
    • SAPKK-3 antibody
    • SAPKK3 antibody
    • SKK3 antibody
    • Stress-activated protein kinase kinase 3 antibody
    see all

Anti-MEK6 antibody images

  • All lanes : Anti-MEK6 antibody (ab71938) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : NIH3T3 cell lysate
    Lane 3 : C6 cell lysate


    Predicted band size : 37 kDa
    Observed band size : 37 kDa

References for Anti-MEK6 antibody (ab71938)

This product has been referenced in:
  • Ortuño MJ  et al. p38 regulates expression of osteoblast-specific genes by phosphorylation of osterix. J Biol Chem 285:31985-94 (2010). WB ; Human . Read more (PubMed: 20682789) »

See 1 Publication for this product

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