Anti-MEK7 (phospho T275) antibody (ab192592)

Overview

  • Product name
    Anti-MEK7 (phospho T275) antibody
    See all MEK7 primary antibodies
  • Description
    Rabbit polyclonal to MEK7 (phospho T275)
  • Specificity
    ab192592 detects endogenous levels of MEK7 only when phosphorylated at threonine 275.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human, African green monkey
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to Human MEK7 (phospho T275) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: O14733

  • Positive control
    • Extracts from COS7 and 3T3 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab192592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 47 kDa.

Target

  • Function
    Stress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.
  • Tissue specificity
    Ubiquitous; with highest level of expression in skeletal muscle. Isoform 3 is found at low levels in placenta, fetal liver, and skeletal muscle.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Activated by phosphorylation on Ser/Thr.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • c-Jun N-terminal kinase kinase 2 antibody
    • Dual specificity mitogen activated protein kinase kinase 7 antibody
    • Dual specificity mitogen-activated protein kinase kinase 7 antibody
    • JNK activating kinase 2 antibody
    • JNK kinase 2 antibody
    • JNK-activating kinase 2 antibody
    • JNKK 2 antibody
    • Jnkk-2 antibody
    • Jnkk2 antibody
    • MAP kinase kinase 7 antibody
    • MAP2K7 antibody
    • MAPK/ERK kinase 7 antibody
    • MAPKK 7 antibody
    • MAPKK-7 antibody
    • MAPKK7 antibody
    • MEK 7 antibody
    • Mitogen Activated Protein Kinase kinase 7 antibody
    • MKK 7 antibody
    • MKK-7 antibody
    • MKK7 antibody
    • MP2K7_HUMAN antibody
    • PRKMK 7 antibody
    • PRKMK-7 antibody
    • PRKMK7 antibody
    • SAPK kinase 4 antibody
    • SAPKK-4 antibody
    • SAPKK4 antibody
    • Sek 2 antibody
    • Sek-2 antibody
    • Sek2 antibody
    • SKK4 antibody
    • stress-activated protein kinase kinase 4 antibody
    see all

Images

  • All lanes : Anti-MEK7 (phospho T275) antibody (ab192592) at 1/500 dilution

    Lane 1 : Extracts from COS7 cells with antigen-specific peptide
    Lane 2 : Extracts from COS7 cells
    Lane 3 : Extracts from 3T3 cells


    Predicted band size : 47 kDa

References

ab192592 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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