Overview

  • Product name
  • Description
    Rabbit polyclonal to MEKK2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to the C-terminal sequence of Human MEKK2. Rat and Mouse sequences differ by one amino acid.

  • Positive control
    • Rat brain tissue lysate, Rat testicular tissus lysate, Rat lung tissue lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 0.1% Dibasic monohydrogen sodium phosphate, 0.45% Sodium chloride, 2.5% BSA, 96.9% Water
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab125223 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 70 kDa. The detection limit is approximately 1ng/lane under non-reducing and reducing conditions.

Target

  • Function
    Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 OPR domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated.
  • Cellular localization
    Cytoplasm. Nucleus. Upon EGF stimulation, translocates into the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • M3K2_HUMAN antibody
    • Map3k2 antibody
    • MAPK/ERK kinase kinase 2 antibody
    • MEK kinase 2 antibody
    • MEKK 2 antibody
    • MEKK2b antibody
    • Mitogen activated protein kinase kinase kinase 2 antibody
    • Mitogen-activated protein kinase kinase kinase 2 antibody
    see all

Images

  • All lanes : Anti-MEKK2 antibody (ab125223) at 1 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat testicular tissue lysate
    Lane 3 : Rat lung tissue lysate


    Predicted band size : 70 kDa

References

ab125223 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab125223.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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