Anti-Melanoma Associated Antigen 100+ / 25kDa antibody [NKI-C3] (ab90739)

Overview

  • Product nameAnti-Melanoma Associated Antigen 100+ / 25kDa antibody [NKI-C3]
    See all Melanoma Associated Antigen 100+ / 25kDa primary antibodies
  • Description
    Mouse Monoclonal [NKI-C3] to Melanoma Associated Antigen 100+ / 25kDa
  • SpecificityNo reaction is seen with basal-cell carcinomas or brain tumours. ab90739 does not react with normal melanocytes or other normal tissues exept for: mast-cells, histiocytes, salivary glands, bronchial glands, pancreatic- and prostatic epithelium. Cross reactivity with carcinoids, medullary carcinomas of the thyroid, and occasionally prostatic-, primary breast-, ovarian- and lung carcinomas, may be observed.
  • Tested applicationsSuitable for: IHC-P, ELISA, ICC, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human Melanoma Associated Antigen 100+/ 25kDa . Immunized with a predominantly intracellular protein of human melanoma cells.

  • Positive control
    • Human Melanoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab90739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/5 - 1/20.
ELISA Use at an assay dependent concentration.
ICC Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Target

  • RelevanceMelanoma-associated antigens (MAAs) are highly immunogenic human antigens that are recognized by cytotoxic T lymphocytes (CTLs). Both ocular and skin melanomas are derived from normal melanocytes that originate from the neural crest, although the melanocytes of the eye are functionally and morphologically distinct. Both types of melanomas carry a wide range of MAAs. Melanoma Associated Antigen 100+ / 25kDa is mainly present in the cytoplasm of melanoma cells and nevocellular nevi.
  • Alternative names
    • Melanoma Associated Antigen antibody

References for Anti-Melanoma Associated Antigen 100+ / 25kDa antibody [NKI-C3] (ab90739)

ab90739 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"