Anti-Melanoma Inhibitory Activity antibody (ab110150)

Overview

• Product nameAnti-Melanoma Inhibitory Activity antibody
  See all Melanoma Inhibitory Activity primary antibodies
• Description
  Rabbit polyclonal to Melanoma Inhibitory Activity
• Tested applicationsSuitable for: IHC-Pmore details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat
• Immunogen

  Synthetic peptide (Human)

• Positive control
  • Human heart tissue

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• Storage bufferpH: 7.40
  Preservative: 0.02% Sodium azide
  Constituents: PBS, 0.88% Sodium chloride, 50% Glycerol
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesab110150 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ClonalityPolyclonal
• IsotypeIgG
• Research areas
  • Immunology
  • Innate Immunity
  • Cytokines
  • Other

  • Signal Transduction
  • Growth Factors/Hormones
  • Hormones

  • Immunology
  • Secreted Molecules
  • Other secreted molecules

  • Cancer
  • Tumor immunology
  • Cytokines
  • Other

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• FunctionElicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
• Tissue specificityAll malignant melanoma cell lines tested and infrequently in glioma cell lines.
• Sequence similaritiesBelongs to the MIA/OTOR family.
  Contains 1 SH3 domain.
• Post-translational
  modificationsMay possess two intramolecular disulfide bonds.
• Cellular localizationSecreted.

• Target information above from: UniProt accession Q16674 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 8190 Human
  • Entrez Gene: 12587 Mouse
  • Entrez Gene: 81510 Rat
  • Omim: 601340 Human
  • SwissProt: Q16674 Human
  • SwissProt: Q61865 Mouse
  • SwissProt: Q62946 Rat
  • Unigene: 646364 Human

  • Unigene: 262447 Mouse
  • Unigene: 10660 Rat

  see all
• Alternative names
  • Cartilage derived retinoic acid sensitive protein antibody
  • CD RAP antibody
  • CDRAP antibody

  • Melanoma derived growth regulatory protein precursor antibody
  • Melanoma inhibitory activity protein antibody
  • Melanoma-derived growth regulatory protein antibody
  • Mia antibody
  • MIA_HUMAN antibody

  see all