Overview

  • Product nameAnti-Melatonin Receptor 1A antibody
    See all Melatonin Receptor 1A primary antibodies
  • Description
    Rabbit polyclonal to Melatonin Receptor 1A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 296-345 (GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV) of Human Melatonin Receptor 1A (NP_005949).

  • Positive control
    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab116337 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionHigh affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
  • Tissue specificityExpressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Mel 1A R antibody
    • MEL-1A-R antibody
    • Mel1a melatonin receptor antibody
    • Mel1a receptor antibody
    • Melatonin receptor 1A antibody
    • Melatonin receptor type 1A antibody
    • MelR antibody
    • MR antibody
    • MT 1 antibody
    • MT1 antibody
    • MTNR 1A antibody
    • MTNR1A antibody
    • MTR1A_HUMAN antibody
    see all

Anti-Melatonin Receptor 1A antibody images

  • Anti-Melatonin Receptor 1A antibody (ab116337) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 39 kDa

References for Anti-Melatonin Receptor 1A antibody (ab116337)

This product has been referenced in:
  • Guo P  et al. Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro. Toxicol Sci N/A:N/A (2014). Human . Read more (PubMed: 25159133) »

See 1 Publication for this product

Product Wall

Application Western blot
Sample Human Tissue lysate - whole (Abdominal endometriotic lesion)
Gel Running Conditions Reduced Denaturing (12% gel)
Loading amount 15 µg
Specification Abdominal endometriotic lesion
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C
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Submitted Mar 21 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"