Anti-Melatonin Receptor 1A antibody (ab176178)

Overview

  • Product name
    Anti-Melatonin Receptor 1A antibody
    See all Melatonin Receptor 1A primary antibodies
  • Description
    Rabbit polyclonal to Melatonin Receptor 1A
  • Tested applications
    Suitable for: Flow Cyt, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Melatonin Receptor 1A aa 209-238 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P48039

  • Positive control
    • CEM cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab176178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/10 - 1/50. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB 1/1000. Predicted molecular weight: 39 kDa.

Target

  • Function
    High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
  • Tissue specificity
    Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Mel 1A R antibody
    • MEL-1A-R antibody
    • Mel1a melatonin receptor antibody
    • Mel1a receptor antibody
    • Melatonin receptor 1A antibody
    • Melatonin receptor type 1A antibody
    • MelR antibody
    • MR antibody
    • MT 1 antibody
    • MT1 antibody
    • MTNR 1A antibody
    • MTNR1A antibody
    • MTR1A_HUMAN antibody
    see all

Images

  • Anti-Melatonin Receptor 1A antibody (ab176178) at 1/1000 dilution + CEM cell lysate at 35 µg

    Predicted band size : 39 kDa
  • Flow cytometric analysis of CEM cells labelling Melatonin Receptor 1A using ab176178 at a 1/10 dilution (green) or negative control (blue). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References

ab176178 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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