Overview

  • Product nameAnti-MELK antibody - C-terminal
    See all MELK primary antibodies
  • Description
    Rabbit polyclonal to MELK - C-terminal
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Positive control
    • HEPG2 tissue lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab71287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 75 kDa).

Target

  • FunctionPhosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.
  • Tissue specificityExpressed in placenta, kidney, thymus, testis, ovary and intestine.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
    Contains 1 KA1 (kinase-associated) domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications
    Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI327312 antibody
    • hMELK antibody
    • HPK 38 antibody
    • hPK38 antibody
    • KIAA0175 antibody
    • Likely ortholog of maternal embryonic leucine zipper kinase antibody
    • Maternal embryonic leucine zipper kinase antibody
    • MELK antibody
    • MELK_HUMAN antibody
    • mKIAA0175 antibody
    • MPK38 antibody
    • OTTHUMP00000021377 antibody
    • OTTHUMP00000046113 antibody
    • pEg3 kinase antibody
    • Protein kinase Eg3 antibody
    • Protein kinase PK38 antibody
    • RP23 382O11.1 antibody
    • Tyrosine protein kinase MELK antibody
    see all

Anti-MELK antibody - C-terminal images

  • Anti-MELK antibody - C-terminal (ab71287) at 1/100 dilution + HEPG2 tissue lysate at 12.5 µg

    Predicted band size : 75 kDa
    Observed band size : 75 kDa
    Additional bands at : 20 kDa,50 kDa. We are unsure as to the identity of these extra bands.

References for Anti-MELK antibody - C-terminal (ab71287)

ab71287 has not yet been referenced specifically in any publications.

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