Recombinant
RabMAb

Anti-MEMO1 antibody [EPR5791] (ab124901)

Overview

  • Product name
    Anti-MEMO1 antibody [EPR5791]
    See all MEMO1 primary antibodies
  • Description
    Rabbit monoclonal [EPR5791] to MEMO1
  • Tested applications
    Suitable for: WB, IP, IHC-P, Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human MEMO1.

  • Positive control
    • Human heart and PC12 lysates; Human breast carcinoma tissue.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab124901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
IP 1/10 - 1/100.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Flow Cyt 1/100 - 1/500.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

ICC/IF 1/100 - 1/250.

Target

  • Function
    May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
  • Sequence similarities
    Belongs to the MEMO1 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • C21orf19-like protein antibody
    • C2orf4 antibody
    • CGI 27 antibody
    • DKFZp434I0135 antibody
    • FLJ25031 antibody
    • HCV NS5A-transactivated protein 7 antibody
    • Hepatitis C virus NS5A-transactivated protein 7 antibody
    • Mediator of cell motility 1 antibody
    • Mediator of ErbB2-driven cell motility 1 antibody
    • MEMO antibody
    • Memo-1 antibody
    • memo1 antibody
    • MEMO1_HUMAN antibody
    • NS5ATP7 antibody
    • Protein MEMO1 antibody
    see all

Images

  • All lanes : Anti-MEMO1 antibody [EPR5791] (ab124901) at 1/1000 dilution

    Lane 1 : Human heart lysate
    Lane 2 : PC12 lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat anti-Rabbit HRP at 1/2000 dilution

    Predicted band size : 33 kDa
  • ab124901, at 1/50 dilution, staining MEMO1 in Formalin-fixed, Paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.
  • Equilibrium disassociation constant (KD)
    Learn more about KD

    Click here to learn more about KD

References

ab124901 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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