Overview

  • Product nameAnti-Mephalan antibody [MP5/73]
  • Description
    Rat monoclonal [MP5/73] to Mephalan
  • SpecificityThis antibody was developed to improve detection of melphalan-DNA adducts through its ability to recognise the stabilised adduct. This antibodiy can be used for quantification of melphalan adducts in purified DNA by ELISA and for immunofluorescent detection of melphalan-DNA adducts in single cells.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Native DNA reacted with melphalan.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityIgG fraction
  • ClonalityMonoclonal
  • Clone numberMP5/73
  • MyelomaY3/Ag1.2.3
  • IsotypeIgG2b
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab97892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • RelevanceMephalan hydrochloride is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.

References for Anti-Mephalan antibody [MP5/73] (ab97892)

This product has been referenced in:
  • Rothbarth J  et al. Immunohistochemical detection of melphalan-DNA adducts in colon cancer cells in vitro and human colorectal liver tumours in vivo. Biochem Pharmacol 67:1771-8 (2004). Read more (PubMed: 15081876) »
  • Frank AJ & Tilby MJ Quantification of DNA adducts in individual cells by immunofluorescence: effects of variation in DNA conformation. Exp Cell Res 283:127-34 (2003). Read more (PubMed: 12581733) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"