Anti-MERTK antibody [Y323] (ab52968)

Publishing research using ab52968? Please let us know so that we can cite the reference in this datasheet.

ab52968 has been referenced in 24 publications.

  • Kariolis MS  et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest 127:183-198 (2017). WB ; Human . PubMed: 27893463
  • Frejno M  et al. Pharmacoproteomic characterisation of human colon and rectal cancer. Mol Syst Biol 13:951 (2017). PubMed: 29101300
  • Petta S  et al. MERTK rs4374383 polymorphism affects the severity of fibrosis in non-alcoholic fatty liver disease. J Hepatol 64:682-90 (2016). WB, IF, IHC ; Human . PubMed: 26596542
  • Minson KA  et al. The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia. JCI Insight 1:e85630 (2016). WB ; Human . PubMed: 27158668
  • Sufit A  et al. MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme. PLoS One 11:e0165107 (2016). WB, IP ; Human . PubMed: 27783662
  • Carter DA  et al. Mislocalisation of BEST1 in iPSC-derived retinal pigment epithelial cells from a family with autosomal dominant vitreoretinochoroidopathy (ADVIRC). Sci Rep 6:33792 (2016). PubMed: 27653836
  • Faltermeier CM  et al. Functional screen identifies kinases driving prostate cancer visceral and bone metastasis. Proc Natl Acad Sci U S A 113:E172-81 (2016). PubMed: 26621741
  • Bernsmeier C  et al. Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK. Gastroenterology 148:603-615.e14 (2015). IHC-P ; Human . PubMed: 25479139
  • Roggia MF & Ueta T avß5 Integrin/FAK/PGC-1a Pathway Confers Protective Effects on Retinal Pigment Epithelium. PLoS One 10:e0134870 (2015). WB, Functional Studies ; Human . PubMed: 26244551
  • Cummings CT  et al. Small Molecule Inhibition of MERTK Is Efficacious in Non-Small Cell Lung Cancer Models Independent of Driver Oncogene Status. Mol Cancer Ther 14:2014-22 (2015). WB . PubMed: 26162689
  • Lee-Sherick AB  et al. Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia. Oncotarget 6:6722-36 (2015). WB ; Human . PubMed: 25762638
  • Xie S  et al. Mer receptor tyrosine kinase is frequently overexpressed in human non-small cell lung cancer, confirming resistance to erlotinib. Oncotarget 6:9206-19 (2015). WB ; Human . PubMed: 25826078
  • Knubel KH  et al. MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme. Oncotarget 5:1338-51 (2014). PubMed: 24658326
  • Pierce AM & Keating AK TAM receptor tyrosine kinases: Expression, disease and oncogenesis in the central nervous system. Brain Res 1542:206-20 (2014). WB . PubMed: 24184575
  • Ranganathan V  et al. Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs. Nat Commun 5:4516 (2014). PubMed: 25105359
  • Brandao LN  et al. Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia. Blood Cancer J 3:e101 (2013). WB ; Human . PubMed: 23353780
  • Lee-Sherick AB  et al. Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia. Oncogene N/A:N/A (2013). WB ; Human . PubMed: 23474756
  • Schlegel J  et al. MERTK receptor tyrosine kinase is a therapeutic target in melanoma. J Clin Invest 123:2257-67 (2013). IHC-P ; Human . PubMed: 23585477
  • Wang Y  et al. Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme. Oncogene : (2012). PubMed: 22469987
  • Migdall-Wilson J  et al. Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus. PLoS One 7:e31635 (2012). WB, ICC/IF ; Human . PubMed: 22363695
  • Deng WT  et al. Tyrosine-mutant AAV8 delivery of human MERTK provides long-term retinal preservation in RCS rats. Invest Ophthalmol Vis Sci 53:1895-904 (2012). PubMed: 22408006
  • Garbin U  et al. Expansion of necrotic core and shedding of Mertk receptor in human carotid plaques: a role for oxidized polyunsaturated fatty acids? Cardiovasc Res : (2012). IHC ; Human . PubMed: 22997156
  • McGill TJ  et al. Transplantation of human central nervous system stem cells - neuroprotection in retinal degeneration. Eur J Neurosci 35:468-77 (2012). PubMed: 22277045
  • Carr AJ  et al. Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay. Mol Vis 15:283-95 (2009). WB, Blocking . PubMed: 19204785


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