Overview

  • Product name
    Anti-Mesothelial cells antibody [HBME-1]
  • Description
    Mouse monoclonal [HBME-1] to Mesothelial cells
  • Host species
    Mouse
  • Specificity
    Staining pattern: Cytoplasmic, Membranous
  • Tested applications
    Suitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human Mesothelial cells.

  • Positive control
    • Human Mesothelioma, Human Thyroid Carcinoma
  • General notes


    ab101139 has been demonstrated to label mesothelial cells, both benign and malignant (malignant mesotheloma) and thus has been used in distinguishing mesothelioma from adenocarcinomas of various origins. More recently this antibody has been used to distinguish Thyroid carcinomas (both Follicular and Papillary) from benign thyroid lesions.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Purity
    Tissue culture supernatant
  • Primary antibody notes
    ab101139 has been demonstrated to label mesothelial cells, both benign and malignant (malignant mesotheloma) and thus has been used in distinguishing mesothelioma from adenocarcinomas of various origins. More recently this antibody has been used to distinguish Thyroid carcinomas (both Follicular and Papillary) from benign thyroid lesions.
  • Clonality
    Monoclonal
  • Clone number
    HBME-1
  • Isotype
    IgM
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab101139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.
IHC-Fr 1/25 - 1/100.

Target

  • Relevance
    Mesothelial cells form a monolayer of cells that line the body's serous cavities and internal organs. The primary function of this layer is to provide a slippery, non-adhesive and protective surface.

References

This product has been referenced in:
  • Qiao J  et al. HBME-1 expression in differentiated thyroid carcinoma and its correlation with the ultrasonic manifestation of thyroid. Oncol Lett 14:6505-6510 (2017). Read more (PubMed: 29151906) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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