Anti-Mesothelioma antibody [HBME-1] (ab2383)

Overview

  • Product nameAnti-Mesothelioma antibody [HBME-1]
    See all Mesothelioma primary antibodies
  • Description
    Mouse monoclonal [HBME-1] to Mesothelioma
  • SpecificityThis antibody reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesothelimias in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Suspension of human mesothelioma cells from patients with malignant epithelial mesothelioma.

  • Positive control
    • Mesothelioma.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA
  • Concentration information loading...
  • PurityPurified IgM
  • ClonalityMonoclonal
  • Clone numberHBME-1
  • Myelomaunknown
  • IsotypeIgM
  • Light chain typeunknown
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2383 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notesIHC: This antibody may be diluted to a titer of 1:12-1:25 in an ABC method.
    We suggest an incubation period of 60 minutes at room temperature.
    However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user.
    Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
  • Target

    • RelevanceMesothelioma is a rare form of carcinoma of the mesothelial cells which that normally line the body cavities, including the pleura, peritoneum, pericardium, and testis. It may be localized or diffuse. Most, but not all, cases of pleural malignant mesothelioma are associated with asbestos exposure.
    • Alternative names
      • Malignant mesothelioma susceptibility to antibody
      • MMS antibody

    Anti-Mesothelioma antibody [HBME-1] images

    • ab2383 staining human mesothelioma by IHC-P.
    • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human mesothelioma tissue, staining Mesothelioma with ab2383.

    References for Anti-Mesothelioma antibody [HBME-1] (ab2383)

    ab2383 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting Abcam regarding ab2383.


    The average concentration of this antibody is 45mg/L. If you have a specific lot number, I can check for that concentration as well.


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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"