Anti-Metabotropic Glutamate Receptor 1 antibody (ab27199)

Overview

  • Product nameAnti-Metabotropic Glutamate Receptor 1 antibody
    See all Metabotropic Glutamate Receptor 1 primary antibodies
  • Description
    Rabbit polyclonal to Metabotropic Glutamate Receptor 1
  • SpecificityThis antibody is specific to Metabotropic Glutamate Receptor 1.
  • Tested applicationsSuitable for: IHC-FoFr, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Chicken, Monkey
  • Immunogen

    Synthetic peptide (Human)(C terminus) (intracellular domain)

  • Positive control
    • Human brain for Immunohistochemistry.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 1% BSA, 10mM PBS, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesThis antibody is affinity purified.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab27199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration. PubMed: 17455332
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • FunctionReceptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 3 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Glutamate receptor metabotropic 1 antibody
    • glutamate receptor, metabotropic 1 antibody
    • GPRC1A antibody
    • GRM1 antibody
    • GRM1-Alpha antibody
    • GRM1_HUMAN antibody
    • GRM1A antibody
    • Metabotropic glutamate receptor 1 antibody
    • mGlu1 antibody
    • mGluR1 antibody
    • MGLUR1-Alpha antibody
    • MGLUR1A antibody
    • SCAR13 antibody
    see all

Anti-Metabotropic Glutamate Receptor 1 antibody images

  • Ab27199 at a dilution of 1/50, staining metabolic glutamate recepor 1 in paraffin embedded formalin fixed human brain tissue section.

References for Anti-Metabotropic Glutamate Receptor 1 antibody (ab27199)

This product has been referenced in:
  • Yip D  et al. A phase 0 trial of riluzole in patients with resectable stage III and IV melanoma. Clin Cancer Res 15:3896-902 (2009). IHC-P ; Human . Read more (PubMed: 19458050) »
  • Minneci F  et al. Signaling properties of stratum oriens interneurons in the hippocampus of transgenic mice expressing EGFP in a subset of somatostatin-containing cells. Hippocampus 17:538-53 (2007). IHC-FoFr ; Mouse . Read more (PubMed: 17455332) »

See all 2 Publications for this product

Product Wall

Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample Rat Tissue sections (Brain - Striatum)
Specification Brain - Striatum
Username

Dr. Sophie Pezet

Verified customer

Submitted Aug 18 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"