Anti-Metabotropic Glutamate Receptor 2 antibody (ab118447)

Overview

  • Product nameAnti-Metabotropic Glutamate Receptor 2 antibody
    See all Metabotropic Glutamate Receptor 2 primary antibodies
  • Description
    Rabbit polyclonal to Metabotropic Glutamate Receptor 2
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region from the N-terminal extracellular domain of Human Metabotropic Glutamate Receptor 2.

  • Positive control
    • Human Brain, Thalamus tissue

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab118447 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionReceptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
  • Tissue specificityWidely expressed in different regions of the adult brain as well as in fetal brain.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 3 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AMPA selective glutamate receptor 2 antibody
    • GLUR2 antibody
    • GLURB antibody
    • Glutamate metabotropic receptor 2 antibody
    • Glutamate receptor homolog antibody
    • Glutamate receptor metabotropic 2 antibody
    • GPRC1B antibody
    • GRM2 antibody
    • GRM2_HUMAN antibody
    • Metabotropic glutamate receptor 2 antibody
    • mGlu2 antibody
    • mGluR2 antibody
    • OTTHUMP00000210984 antibody
    • OTTHUMP00000210986 antibody
    see all

Anti-Metabotropic Glutamate Receptor 2 antibody images

  • Human Brain, Thalamus (formalin-fixed, paraffin-embedded) stained with ab118447 at 4 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-Metabotropic Glutamate Receptor 2 antibody (ab118447)

ab118447 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step Commercial Peroxidase blocking buffer as blocking agent for 5 minute(s) · Concentration: 100% · Temperature: RT°C
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Commercial High pH Buffer
Sample Human Tissue sections (Tendon)
Specification Tendon
Permeabilization No
Fixative Formaldehyde
Username

Dr. Sarah Franklin

Verified customer

Submitted Aug 14 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"