Anti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s] (ab15672)


  • Product nameAnti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s]
    See all Metabotropic Glutamate Receptor 2 primary antibodies
  • Description
    Mouse monoclonal [mG2Na-s] to Metabotropic Glutamate Receptor 2
  • SpecificityThis antibody recognizes the metabotrophic glutamate receptor 2, but not metabotrophic glutamate receptor 3.
  • Tested applicationsSuitable for: IHC-Fr, WB, ICC/IF, IHC-FoFrmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Fusion protein corresponding to Metabotropic Glutamate Receptor 2. Fusion protein contains a 47 amino acid sequence of the N terminal of the Metabotrophic Glutamate Receptor 2


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.4 sterile filtered
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numbermG2Na-s
  • IsotypeIgG
  • Research areas


Our Abpromise guarantee covers the use of ab15672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use a concentration of 1 µg/ml. See reference Neki et al, Neurosci Letts.
WB Use a concentration of 1 µg/ml. Detects a band of approximately 99 kDa (predicted molecular weight: 104 kDa). See reference Neki et al, Neurosci Letts.
ICC/IF Use at an assay dependent concentration.
IHC-FoFr Use at an assay dependent dilution.


  • FunctionReceptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
  • Tissue specificityWidely expressed in different regions of the adult brain as well as in fetal brain.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 3 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AMPA selective glutamate receptor 2 antibody
    • GLUR2 antibody
    • GLURB antibody
    • Glutamate metabotropic receptor 2 antibody
    • Glutamate receptor homolog antibody
    • Glutamate receptor metabotropic 2 antibody
    • GPRC1B antibody
    • GRM2 antibody
    • GRM2_HUMAN antibody
    • Metabotropic glutamate receptor 2 antibody
    • mGlu2 antibody
    • mGluR2 antibody
    • OTTHUMP00000210984 antibody
    • OTTHUMP00000210986 antibody
    see all

Anti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s] images

  • Anti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s] (ab15672) at 1 µg/ml + Brain (Rat) Tissue Lysate at 10 µg

    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 104 kDa
    Observed band size : 99 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 12 minutes
  • Immunohistochemical analysis of mouse cortical neurons, staining Metabotropic Glutamate Receptor 2 with ab15672. Donkey anti-mouse 6-nm colloidal gold particles were used to detect staining. Images were visualized by electron microscopy.

References for Anti-Metabotropic Glutamate Receptor 2 antibody [mG2Na-s] (ab15672)

This product has been referenced in:
  • Kurita M  et al. Repressive epigenetic changes at the mGlu2 promoter in frontal cortex of 5-HT2A knockout mice. Mol Pharmacol 83:1166-75 (2013). Read more (PubMed: 23508685) »
  • Konermann S  et al. Optical control of mammalian endogenous transcription and epigenetic states. Nature 500:472-6 (2013). Read more (PubMed: 23877069) »

See all 12 Publications for this product

Product Wall

Application Western blot
Sample Human Tissue lysate - whole (Human brain lysate)
Gel Running Conditions Reduced Denaturing (Samples heated 5 min at 37 degrees, 4%-15% gel)
Loading amount 10 µg
Specification Human brain lysate
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C

Abcam user community

Verified customer

Submitted Oct 11 2016

You are correct, this antibody recognizes a portion of the N-terminus of mGluR2.

I am glad to read that most of the antibodies you ordered are giving good results. For the two that are not, could you please send some details of the samples and protocols and results? In particular, we would like to know the species, the time in PFA,...

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Gracias por tu respuesta.

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