Anti-Metabotropic Glutamate Receptor 7 antibody (ab85343)

Overview

  • Product name
    Anti-Metabotropic Glutamate Receptor 7 antibody
    See all Metabotropic Glutamate Receptor 7 primary antibodies
  • Description
    Goat polyclonal to Metabotropic Glutamate Receptor 7
  • Specificity
    ab85343 is expected to recognize both reported isoforms (NP_000835.1; NP_870989.1).
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide:

    NCKLTISGSKKEDT

    , corresponding to internal sequence amino acids 373-386 of Human Metabotropic Glutamate Receptor 7 (NP_000835.1; NP_870989.1)

  • Positive control
    • Human Brain (Cerebellum), Mouse and Rat Brain lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab85343 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab85343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 102 kDa (predicted molecular weight: 102 kDa).

Target

  • Function
    Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
  • Tissue specificity
    Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 3 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ40498 antibody
    • GLUR7 antibody
    • Glutamate receptor metabotropic 7 antibody
    • GPRC1G antibody
    • GRM7 antibody
    • GRM7_HUMAN antibody
    • Metabotropic glutamate receptor 7 antibody
    • MGLU7 antibody
    • mGluR7 antibody
    • OTTHUMP00000206961 antibody
    • OTTHUMP00000214674 antibody
    • OTTHUMP00000214675 antibody
    see all

Images

  • Anti-Metabotropic Glutamate Receptor 7 antibody (ab85343) at 0.5 µg/ml + Human Cerebellum lysate at 35 µg

    Predicted band size : 102 kDa
    Observed band size : 102 kDa

References

ab85343 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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