Anti-Metallophilic Macrophages antibody [MOMA-1] (FITC) (ab34355)

Overview

  • Product name
    Anti-Metallophilic Macrophages antibody [MOMA-1] (FITC)
    See all Metallophilic Macrophages primary antibodies
  • Description
    Rat monoclonal [MOMA-1] to Metallophilic Macrophages (FITC)
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Specificity
    ab34355 reacts with a subpopulation of mature resident tissue macrophages.
  • Tested applications
    Suitable for: ICC/IF, IHC-Fr, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
    Does not react with: Rat, Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    MOMA-1
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab34355 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24706909
IHC-Fr Use at an assay dependent concentration.
Flow Cyt 1/1. ab18446-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Relevance
    Metallophilic macrophages are a subpopulation of mature resident tissue macrophages. They show high non specific esterase activity and can be distinguished from splenic marginal zone macrophages by antibody staining and the lack of FITC-Ficoll uptake.

References

This product has been referenced in:
  • Inoue M  et al. T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation. Proc Natl Acad Sci U S A 111:5295-300 (2014). ICC/IF ; Mouse . Read more (PubMed: 24706909) »
  • Pabst O  et al. NKX2.3 is required for MAdCAM-1 expression and homing of lymphocytes in spleen and mucosa-associated lymphoid tissue. EMBO J 19:2015-23 (2000). Read more (PubMed: 10790368) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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