Anti-Methamphetamine antibody [M352009] (ab47866)

Overview

  • Product nameAnti-Methamphetamine antibody [M352009]
    See all Methamphetamine primary antibodies
  • Description
    Mouse monoclonal [M352009] to Methamphetamine
  • SpecificitySpecific for methamphetamine.
  • Tested applicationsSuitable for: Conjugationmore details
  • Immunogen

    Methamphetamine-4-BSA.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab47866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Conjugation
  • Application notesConjugation: Use at an assay dependent dilution.
    Recommended for Lateral/Gold conjugation applications.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceMethamphetamine (METH) is closely related chemically to amphetamine (AMPH). METH is a potent central nervous system stimulant with additional peripheral sympathomimetic effects. METH and AMPH have been used clinically in the treatment of obesity, minimal brain dysfunction, narcolepsy, depression and to counter fatigue. They are also subjected to widespread abuse. METH is an indirect agonists. It causes the release of newly synthesized norepinephrine and dopamine and it blocks the re uptake of these transmitters from the synapse. This can lead to an increase in the concentration of catecholamines in the synapse as well as an overall increase in catecholaminergic activity in the brain. The mechanism of METH induced neurotoxicity for all monoaminergic cell types may lie primarily with the dopaminergic system in the striatum. It may also lie with the interaction between METH induced release of dopamine and its ability to inhibit monoamine oxidase.
    • Alternative names
      • METH antibody

    References for Anti-Methamphetamine antibody [M352009] (ab47866)

    ab47866 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"