The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent dilution.
FunctionHas an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
Tissue specificityUbiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus.
Sequence similaritiesBelongs to the MsrA Met sulfoxide reductase family.
Cellular localizationCytoplasm; Cytoplasm. Nucleus and Mitochondrion.