Specificityab53524 recognises proteins methylated on lysine residues (mono and di-methylysine). It does not cross-react with acetylated proteins. Cross-reactivity with tri-methyllysine has not been tested.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: 1/1000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceMany proteins are post translationally modified. Modifications such as phosphorylation, glycosylation, ubiquitination and methylation have been shown to play an important role in the development, physiology and disease of animals and plants.
Histone lysine methylation is regarded as a very stable modification with important functions in epigenetic gene control and for organizing chromatin domains.
Methyl lysine antibody
N epsilon dimethyl lysine antibody
N epsilon mono methyllysine antibody
N epsilon trimethyl lysine antibody
N(epsilon) trimethyl lysine antibody
Trimethyl lysine antibody
References for Anti-Methylated Lysine antibody (Biotin) (ab53524)
has not yet been referenced specifically in any publications.
Publishing research using ab53524? Please let us know so that we can cite the reference in this datasheet.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"