Overview

  • Product name
    Methysergide maleate
  • Description
    5-HT receptor antagonist
  • Alternative names
    • UML-491
  • Biological description
    5-HT receptor antagonist (Ki values are 10 and 2.5 nM at 5-HT2A and 5-HT2C receptors, respectively). Displays antimigraine activity.
  • Purity
    > 99%

Properties

References

This product has been referenced in:
  • Pytliak M  et al. Serotonin receptors - from molecular biology to clinical applications. Physiol Res 60:15-25 (2011). Read more (PubMed: 20945968) »
  • Hedner E  et al. Brominated cyclodipeptides from the marine sponge Geodia barretti as selective 5-HT ligands. J Nat Prod 69:1421-4 (2006). Read more (PubMed: 17067154) »
  • Schmuck K  et al. Activation of meningeal 5-HT2B receptors: an early step in the generation of migraine headache? Eur J Neurosci 8:959-67 (1996). Read more (PubMed: 8743744) »

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