Overview

  • Product name
  • Description
    Rabbit polyclonal to METTL1
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Chimpanzee, Cynomolgus monkey, Rhesus monkey, Gorilla, Opossum, Chinese hamster, Common marmoset, Orangutan, Platypus
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 175-225 of Human METTL1 (NP_005362.3).

  • Positive control
    • 293T, HeLa, Jurkat, and TCMK-1 whole cell lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab157097 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 31 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
    • Tissue specificity
      Ubiquitous.
    • Pathway
      tRNA modification; N(7)-methylguanine-tRNA biosynthesis.
    • Sequence similarities
      Belongs to the methyltransferase superfamily. TrmB family.
    • Post-translational
      modifications
      Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • C12orf1 antibody
      • D1075 like gene product antibody
      • FLJ95748 antibody
      • Methyltransferase like 1 antibody
      • Methyltransferase like protein 1 antibody
      • Methyltransferase-like protein 1 antibody
      • Mettl1 antibody
      • TRM8 antibody
      • TRMB_HUMAN antibody
      • TRMT8 antibody
      • tRNA (guanine N(7) ) methyltransferase antibody
      • tRNA (guanine(46)-N(7))-methyltransferase antibody
      • tRNA (guanine-N(7)-)-methyltransferase antibody
      • tRNA(m7G46) methyltransferase antibody
      • tRNA(m7G46)-methyltransferase antibody
      • YDL201w antibody
      see all

    Images

    • All lanes : Anti-METTL1 antibody (ab157097) at 0.4 µg/ml

      Lane 1 : 293T whole cell lysate
      Lane 2 : HeLa whole cell lysate
      Lane 3 : Jurkat whole cell lysate
      Lane 4 : TCMK-1 whole cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique

      Predicted band size : 31 kDa


      Exposure time : 3 minutes

    References

    ab157097 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab157097.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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