Overview

  • Product nameAnti-METTL1 antibody
    See all METTL1 primary antibodies
  • Description
    Mouse polyclonal to METTL1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human METTL1, amino acids 1-276 (AAH00550)

  • Positive control
    • Human placenta tissue lysate, METTL1 transfected 293T cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab88912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.

Target

  • FunctionCatalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  • Tissue specificityUbiquitous.
  • PathwaytRNA modification; N(7)-methylguanine-tRNA biosynthesis.
  • Sequence similaritiesBelongs to the methyltransferase superfamily. TrmB family.
  • Post-translational
    modifications
    Phosphorylation at Ser-27 inactivates its catalytic activity but does not affect the interaction with WDR4.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • C12orf1 antibody
    • D1075 like gene product antibody
    • FLJ95748 antibody
    • Methyltransferase like 1 antibody
    • Methyltransferase like protein 1 antibody
    • Methyltransferase-like protein 1 antibody
    • Mettl1 antibody
    • TRM8 antibody
    • TRMB_HUMAN antibody
    • TRMT8 antibody
    • tRNA (guanine N(7) ) methyltransferase antibody
    • tRNA (guanine(46)-N(7))-methyltransferase antibody
    • tRNA (guanine-N(7)-)-methyltransferase antibody
    • tRNA(m7G46) methyltransferase antibody
    • tRNA(m7G46)-methyltransferase antibody
    • YDL201w antibody
    see all

Anti-METTL1 antibody images

  • Anti-METTL1 antibody (ab88912) at 1/500 dilution + Human placenta tissue lysate at 50 µg

    Predicted band size : 31 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-METTL1 antibody (ab88912) at 1/500 dilution

    Lane 1 : METTL1 transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 31 kDa
    Observed band size : 31 kDa

References for Anti-METTL1 antibody (ab88912)

ab88912 has not yet been referenced specifically in any publications.

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