Overview

  • Product name
  • Description
    Rabbit polyclonal to MFI2
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, from the N terminal region of Human MFI2.

  • Positive control
    • Human prostate and Human brain (cortex) tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab115334 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 15 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
  • Tissue specificity
    Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.
  • Sequence similarities
    Belongs to the transferrin family.
    Contains 2 transferrin-like domains.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen p97 antibody
    • CD228 antibody
    • CD228 antigen antibody
    • MAP97 antibody
    • Melanoma associated antigen p97 antibody
    • Melanoma-associated antigen p97 antibody
    • Melanotransferrin antibody
    • Mfi2 antibody
    • MTF1 antibody
    • TRFM_HUMAN antibody
    see all

Images

  • ab115334 at 15ug/ml staining MFI2 in Formalin-fixed, Paraffin-embedded Human prostate tissue by Immunohistochemistry followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • ab115334 at 15ug/ml staining MFI2 in Formalin-fixed, Paraffin-embedded Human brain cortex by Immunohistochemistry followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115334 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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