The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesWB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
RelevanceMembrane frizzled-related protein, MFRP, may have a role in eye development and may be necessary for photoreceptor maintenance. Mutations of membrane-type frizzled-related protein are associated with inherited retinal degenerations including syndromic forms of microphthalmos/retinal degeneration, a rare autosomal recessive disorder of eye development characterized by extreme hyperopia and small functional eyes,posterior microphthalmia with retinitis pigmentosa, foveoschisis, and optic disk drusen.
Cellular localizationCell Membrane; single-pass type II membrane protein