Overview

  • Product name
    Anti-MGAT5B antibody
  • Description
    Rabbit polyclonal to MGAT5B
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 362-411 (EGPAPLEAIA NGCIFLQSRF SPPHSSLNHE FFRGKPTSRE VFSQHPYAEN) of Rat MGAT5B (NP_001100538.1).

  • Positive control
    • Rat Muscle Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab125403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 90 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
  • Tissue specificity
    Predominantly expressed in brain. Expressed in all area of the adult and fetal brain Also expressed at much lower level in testis, spleen and thymus.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 18 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B antibody
    • 6-N-acetylglucosaminyltransferase B antibody
    • Alpha-1 antibody
    • Alpha-mannoside beta-1 antibody
    • GlcNAc-T Vb antibody
    • GNT-IX antibody
    • GNT-Vb antibody
    • hGnTVb antibody
    • Mannoside acetylglucosaminyltransferase 5B antibody
    • Mgat5b antibody
    • MGT5B_HUMAN antibody
    • N-acetylglucosaminyl-transferase Vb antibody
    • N-acetylglucosaminyltransferase IX antibody
    see all

Images

  • Anti-MGAT5B antibody (ab125403) at 1 µg/ml + Rat Muscle Lysate

    Predicted band size : 90 kDa

References

ab125403 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab125403.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up