Overview

  • Product nameAnti-MGP antibody
    See all MGP primary antibodies
  • Description
    Mouse polyclonal to MGP
  • SpecificityThis antibody is reactive against mammalian transfected lysate.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    MGP (AAH93078.1, 1 a.a. ~ 103 a.a) full-length human protein.

  • Positive control
    • Transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab70193 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).

Target

  • FunctionAssociates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
  • Involvement in diseaseDefects in MGP are the cause of Keutel syndrome (KS) [MIM:245150]. KS is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
  • Sequence similaritiesBelongs to the osteocalcin/matrix Gla protein family.
    Contains 1 Gla (gamma-carboxy-glutamate) domain.
  • Post-translational
    modifications
    Requires vitamin K-dependent gamma-carboxylation for its function.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cell growth inhibiting gene 36 protein antibody
    • Cell growth-inhibiting gene 36 protein antibody
    • GAMMA-CARBOXYGLUTAMIC ACID PROTEIN, MATRIX antibody
    • GIG36 antibody
    • Matrix Gla protein antibody
    • MGLAP antibody
    • MGP antibody
    • MGP_HUMAN antibody
    • NTI antibody
    see all

Anti-MGP antibody images

  • All lanes : Anti-MGP antibody (ab70193) at 1/500 dilution

    Lane 1 : MGP transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 12 kDa
    Observed band size : 12 kDa

References for Anti-MGP antibody (ab70193)

ab70193 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The anti-MGP antibody (ab70193) has been raised against the full length MGP protein and as it is a polyclonal antibody the exact epitope cannot be determined.We would expect theantibodyto be able to detectboth for...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"