Anti-MHC Class I H2 Kb + Db antibody [5041.16.1] (Phycoerythrin) (ab112492)

Overview

  • Product name
    Anti-MHC Class I H2 Kb + Db antibody [5041.16.1] (Phycoerythrin)
    See all MHC Class I H2 Kb + Db primary antibodies
  • Description
    Mouse monoclonal [5041.16.1] to MHC Class I H2 Kb + Db (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Thymus, lymph node and spleen cells from a bm12 mutant mouse.

  • Positive control
    • Mouse spleen cells (C57BL/6 strain).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab112492 is purified from ascitic fluid via Protein G Chromatography.
  • Clonality
    Monoclonal
  • Clone number
    5041.16.1
  • Myeloma
    NS1
  • Isotype
    IgG2a
  • Light chain type
    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab112492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.2-0.5µg for 106 cells. ab91363-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Relevance
    In the mouse the MHC Class 1 loci are called H2K, H2L and H2D. The equivalent loci in the human MHC are HLA (Human Leukocyte Antigen). MHC class I molecules are heterodimers, consisting of a single transmembrane polypeptide chain (the a-chain) which is highly polymorphic, and the invariant ß2 microglobulin (which is encoded elsewhere, not in the MHC). MHC class I molecules are found on almost every nucleated cell of the body. Their major function is to present peptide fragments derived from antigens to cytotoxic T cells.
  • Cellular localization
    Membrane; Single-pass type I membrane protein.
  • Database links
  • Alternative names
    • H 2 class I histocompatibility antigen, D B alpha chain antibody
    • H 2 class I histocompatibility antigen, K B alpha chain antibody
    • H 2D antibody
    • H 2K antibody
    • H 2K(d) antibody
    • H2 D antibody
    • H2 D1 antibody
    • H2 K antibody
    • H2-K1 antibody
    • Histocompatibility 2, D region locus 1 antibody
    • Histocompatibility 2, K1, K region antibody
    • K f antibody
    • MGC184092 antibody
    • MGC7052 antibody
    see all

Anti-MHC Class I H2 Kb + Db antibody [5041.16.1] (Phycoerythrin) images

  • ab112492 at 0.2µg/106 cells staining MHC Class I H2 Kb + Db in Mouse spleen cells (C57BL/6 strain) by Flow Cytometry.
    Percentage of cells stained above control (PE Mouse IgG2a, k): 99.3.

References for Anti-MHC Class I H2 Kb + Db antibody [5041.16.1] (Phycoerythrin) (ab112492)

ab112492 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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