Anti-MHC class I RT Ia antibody [MRC OX-27] (Biotin) (ab111923)


  • Product nameAnti-MHC class I RT Ia antibody [MRC OX-27] (Biotin)
    See all MHC class I RT Ia primary antibodies
  • Description
    Mouse monoclonal [MRC OX-27] to MHC class I RT Ia (Biotin)
  • ConjugationBiotin
  • SpecificityCross-reactivity with Lewis rats have been shown to occur in some instances. ab111923 did not cross-react with Buffalo, Wistar, Fischer and ACI strains in Flow Cytometry.
  • Tested applicationsSuitable for: Flow Cyt, IHC-Frmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Phytohaemagglutinin Blasts.

  • Positive control
    • Rat Spleen cells (Brown Norway strain).


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.02% Sodium azide
    Constituents: 99% PBS, 0.5% BSA
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab111923 was purified from ascitic fluid via Protein G Chromatography.
  • ClonalityMonoclonal
  • Clone numberMRC OX-27
  • MyelomaP3-NS1/1-Ag4-1
  • IsotypeIgG2a
  • Research areas


Our Abpromise guarantee covers the use of ab111923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5-1µg for 106 cells. ab97679-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IHC-Fr Use at an assay dependent concentration.


  • RelevanceThe major histocompatibility complex (MHC) plays a central role in controlling immune responsiveness and susceptibility to a great variety of mainly autoimmune and infectious diseases. The mammalian MHC is usually divided into three regions, the class I, II, and III (also called central) gene regions, based on the genes contained therein. Class I regions encode the classical I (class Ia) and nonclassical I (class Ib) molecules. The widely expressed class Ia molecules perform the well described antigen presenting function to CD8 T lymphocytes, whereas the function of class Ib genes has largely remained unknown.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • RT1 class I gene (A 1) antibody
    • RT1 class I gene antibody
    • RT1 class Ia locus A antibody
    • RT1 class Ia, locus A (A1) antibody
    • RT1 class Ia, locus A1 antibody
    • RT1.A1(N) antibody
    • RT1A 1 antibody
    • RT1A1 antibody
    see all

Anti-MHC class I RT Ia antibody [MRC OX-27] (Biotin) images

  • ab111923 at 1.0 µg/106 cells detecting MHC class I RT Ia in Brown Norway Rat spleen cells by Flow Cytometry. 98.9% more of the cells were stained than in the control (Biotin Mouse IgG2a).

References for Anti-MHC class I RT Ia antibody [MRC OX-27] (Biotin) (ab111923)

ab111923 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your email. We have the following references for Immunohistochemistry that may be of interest to you: Baker-Cairns, B.J. et al. 1996. Contributions of donor and host blood vessels in CNS allografts. Experimental Neurol...

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