Anti-MHC class I RT Ia antibody [MRC OX-27] (FITC) (ab111843)

Overview

  • Product nameAnti-MHC class I RT Ia antibody [MRC OX-27] (FITC)
    See all MHC class I RT Ia primary antibodies
  • Description
    Mouse monoclonal [MRC OX-27] to MHC class I RT Ia (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Phytohaemagglutinin Blasts.

  • Positive control
    • Brown Norway Rat spleen cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferPreservative: 0.02% Sodium azide
    Constituents: 99% PBS, 0.5% BSA
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab111843 was purified from ascitic fluid via Protein G Chromatography.
  • ClonalityMonoclonal
  • Clone numberMRC OX-27
  • MyelomaP3-NS1/1-Ag4-1
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab111843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.2µg for 106 cells. ab91362-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • RelevanceThe major histocompatibility complex (MHC) plays a central role in controlling immune responsiveness and susceptibility to a great variety of mainly autoimmune and infectious diseases. The mammalian MHC is usually divided into three regions, the class I, II, and III (also called central) gene regions, based on the genes contained therein. Class I regions encode the classical I (class Ia) and nonclassical I (class Ib) molecules. The widely expressed class Ia molecules perform the well described antigen presenting function to CD8 T lymphocytes, whereas the function of class Ib genes has largely remained unknown.
  • Cellular localizationSecreted
  • Database links
  • Alternative names
    • RT1 class I gene (A 1) antibody
    • RT1 class I gene antibody
    • RT1 class Ia locus A antibody
    • RT1 class Ia, locus A (A1) antibody
    • RT1 class Ia, locus A1 antibody
    • RT1.A1(N) antibody
    • RT1A 1 antibody
    • RT1A1 antibody
    see all

Anti-MHC class I RT Ia antibody [MRC OX-27] (FITC) images

  • ab111843 at 0.5 µg/10<> cells detecting MHC class I RT Ia in Brown Norway Rat spleen cells by Flow Cytometry. 99% more of the cells were stained than in the control (FITC Mouse IgG2a). Strains Wistar, Buffalo, Fischer and ACI were negative in this assay.

References for Anti-MHC class I RT Ia antibody [MRC OX-27] (FITC) (ab111843)

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"