Anti-MHC Class II I Ak antibody [IA-G3] (ab40970)

Overview

  • Product nameAnti-MHC Class II I Ak antibody [IA-G3]
  • Description
    Mouse monoclonal [IA-G3] to MHC Class II I Ak
  • Tested applicationsSuitable for: Flow Cyt, IPmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Purified mouse lymph node B cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberIA-G3
  • IsotypeIgG2
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab40970 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IP
  • Application notesFlow Cyt: Use 5-10µl for 106 cells.
    IP: Use at an assay dependent dilution.
    May also be used in staining, sorting, panning and antibody mediated cytotoxicity.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceA major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
    • Cellular localizationCell Membrane; single-pass type I membrane protein.
    • Database links
    • Alternative names
      • H 2 class II histocompatibility antigen A K alpha chain antibody
      • H2 Aa antibody
      • H2 Ab1 antibody

    References for Anti-MHC Class II I Ak antibody [IA-G3] (ab40970)

    ab40970 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"