Anti-MHC Class II I E antibody [IE-D6] (ab40974)

Overview

  • Product nameAnti-MHC Class II I E antibody [IE-D6]
    See all MHC Class II I E primary antibodies
  • Description
    Mouse monoclonal [IE-D6] to MHC Class II I E
  • SpecificityThis antibody is specific for MHC Class II I E, I-Ed, I-Ep, I-Er but not for I-Eb.
  • Tested applicationsSuitable for: Flow Cyt, IPmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Purified mouse lymph node B cells.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone numberIE-D6
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab40974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 2.5-5µl for 106 cells. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
May also be used in staining, panning, sorting and antibody mediated cytotoxicity.

Target

  • RelevanceA major histocompatibility complex class II receptor. These display processed antigens from virally infected or transformed cells. Class II positive cells ('antigen presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re export the peptides (now bound to MHC class II protein) to the cell surface. These peptide MHC class II complexes can then be recognized by specific CD4+ lymphocytes.
  • Cellular localizationType I membrane protein; single-pass type I membrane protein
  • Database links
  • Alternative names
    • AI323765 antibody
    • E alpha f antibody
    • H 2 class II histocompatibility antigen E D alpha chain antibody
    • H 2Ea antibody
    • H2 class II histocompatibility antigen E D alpha chain antibody
    • H2 Ea antibody
    • H2 Ea histocompatibility 2 class II antigen E alpha antibody
    • H2 IE alpha antibody
    • H2Ea antibody
    • Histocompatibility 2 class II antigen E alpha antibody
    • I E alpha MHC class II antibody
    • Ia 3 antibody
    • Ia3 antibody
    • Major histocompatibility complex H 2E alpha chain antibody
    • MGC117888 antibody
    • MHC class II antigen E alpha antibody
    see all

References for Anti-MHC Class II I E antibody [IE-D6] (ab40974)

ab40974 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"