Anti-MHC Class II RT1B a + c antibody [MRC OX-76] (ab59866)

Overview

  • Product name
    Anti-MHC Class II RT1B a + c antibody [MRC OX-76]
  • Description
    Mouse monoclonal [MRC OX-76] to MHC Class II RT1B a + c
  • Specificity
    ab59866 is specific to MHC Class II RT1B a+, c+, L-,u-.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    The details of the immunogen for this antibody are not available.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    MRC OX-76
  • Isotype
    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab59866 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: 1/25 - 1/50. Use 10µl of the suggested working dilution to label 106 cells in 100µl.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      MHC Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages) and play a central role in the immune system by presenting peptides derived from extracellular proteins. RT1B may be a gene complex.
    • Cellular localization
      Cell Membrane
    • Database links
    • Alternative names
      • Activated B cell RT1Bl alpha chain antibody
      • MHC class II antigen antibody
      • RT1 class II histocompatibility antigen, A beta chain antibody
      • RT1 class II, locus Ba antibody

    References

    This product has been referenced in:
    • Noailles A  et al. Persistent inflammatory state after photoreceptor loss in an animal model of retinal degeneration. Sci Rep 6:33356 (2016). Read more (PubMed: 27624537) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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