Anti-Milk Fat Globule 1 antibody [SPM291], prediluted (ab54454)

Overview

  • Product nameAnti-Milk Fat Globule 1 antibody [SPM291], prediluted
    See all Milk Fat Globule 1 primary antibodies
  • Description
    Mouse monoclonal [SPM291] to Milk Fat Globule 1, prediluted
  • SpecificityWe have data to indicate that this antibody may not cross react with Rat. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human Milk Fat Globule 1. Delipidated human milk fat globule membrane preparation.

  • Positive control
    • SKBR-3 cells. Breast, colon, or lung tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab54454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: Ready-to-use for 30 min at RT.
    Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.
      Medin is the main constituent of aortic medial amyloid.
    • Tissue specificityMammary epithelial cell surfaces and aortic media. Overexpressed in several carcinomas.
    • Sequence similaritiesContains 1 EGF-like domain.
      Contains 2 F5/8 type C domains.
    • Post-translational
      modifications
      Medin has a ragged N-terminus with minor species starting at Pro-264 and Gly-273.
    • Cellular localizationMembrane. Secreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • BA46 antibody
      • Breast epithelial antigen BA46 antibody
      • EDIL1 antibody
      • HMFG antibody
      • hP47 antibody
      • HsT19888 antibody
      • Lactadherin antibody
      • Medin antibody
      • MFG-E8 antibody
      • MFGE8 antibody
      • MFGM antibody
      • MFGM_HUMAN antibody
      • Milk fat globule EGF factor 8 antibody
      • Milk fat globule EGF factor 8 protein antibody
      • Milk fat globule-EGF factor 8 antibody
      • O acetyl disialoganglioside synthase antibody
      • OAcGD3S antibody
      • SED1 antibody
      • SPAG10 antibody
      • Sperm associated antigen 10 antibody
      • Sperm surface protein hP47 antibody
      see all

    Anti-Milk Fat Globule 1 antibody [SPM291], prediluted images

    • ab54454 (prediluted) staining Human Milk Fat Globule 1 in human colon by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

    References for Anti-Milk Fat Globule 1 antibody [SPM291], prediluted (ab54454)

    ab54454 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"