Overview

  • Product name
  • Description
    Rabbit polyclonal to Mimitin
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A 14 amino acid synthetic peptide from near the carboxy terminus of Human Mimitin (NP_777549).

  • Positive control
    • Raji cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab91521 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notes
    ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 20 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Acts as a molecular chaperone for mitochondrial complex I assembly.
    • Tissue specificity
      Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts.
    • Involvement in disease
      Defects in NDUFAF2 are a cause of mitochondrial complex I deficiency (MT-C1D) [MIM:252010]. A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease.
    • Sequence similarities
      Belongs to the complex I NDUFA12 subunit family.
    • Cellular localization
      Mitochondrion.
    • Information by UniProt
    • Database links
    • Alternative names
      • B17.2 like antibody
      • B17.2-like antibody
      • B17.2L antibody
      • FLJ22398 antibody
      • MIMIT_HUMAN antibody
      • Mimitin antibody
      • Mimitin mitochondrial antibody
      • mitochondrial antibody
      • MMTN antibody
      • Myc induced mitochondrial protein antibody
      • Myc-induced mitochondrial protein antibody
      • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor 2 antibody
      • NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 antibody
      • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 antibody
      • NDUFA12 like antibody
      • NDUFA12 like protein antibody
      • NDUFA12-like protein antibody
      • NDUFA12L antibody
      • NDUFAF2 antibody
      • OTTHUMP00000161882 antibody
      • OTTHUMP00000221703 antibody
      see all

    Images

    • Lane 1 : Anti-Mimitin antibody (ab91521) at 1 µg/ml
      Lane 2 : Anti-Mimitin antibody (ab91521) at 2 µg/ml

      Lane 1 : Raji cell lysate
      Lane 2 : Raji cell lysate

      Lysates/proteins at 15 µg per lane.


      Predicted band size : 20 kDa

    References

    ab91521 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab91521.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up