Anti-Mitochondrial dicarboxylate carrier antibody (ab32632)

Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab32632 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 32 kDa.

Target

  • RelevanceThe mitochondrial dicarboxylate carrier protein (mDIC) belongs to superfamily of mitochondrial transporters. It has been demonstrated that the expression of mDIC leads to hyperpolarization of the mitochondria, as well as succinate uptake by the mitochondria. It is highly expressed in adipose tissue, where its expression is downregulated by insulin and upregulated by free fatty acids. mDIC is also thought to play a role in glyceroneogenesis.
  • Cellular localizationMitochondrion; mitochondrial inner membrane; multi pass membrane protein.
  • Database links
  • Alternative names
    • DIC antibody
    • SLC25A10 antibody
    • Solute carrier family 25 member 10 antibody

References for Anti-Mitochondrial dicarboxylate carrier antibody (ab32632)

ab32632 has not yet been referenced specifically in any publications.

Product Wall

The western blot data for this antibody is in the following reference, which also briefly describes production of the antibody.

Predominant expression of the mitochondrial dicarboxylate carrier in white adipose tissue. Biochem J. 1999 Dec 1;...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"