The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Detects a band of approximately 22 kDa (predicted molecular weight: 28 kDa).
Application notesIs unsuitable for IHC-P or IP.
FunctionStores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Tissue specificityDetected in testis and erythroleukemia. Expression is very low or not detectable in brain, colon, heart, kidney, liver, lung, muscle, placental, spleen and small intestine.
Sequence similaritiesBelongs to the ferritin family. Contains 1 ferritin-like diiron domain.