Overview

  • Product nameAnti-Mitofusin 1 antibody
    See all Mitofusin 1 primary antibodies
  • Description
    Goat polyclonal to Mitofusin 1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from Human Mitofusin 1.

  • Positive control
    • Human Adrenal and Human Uterus tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab111271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionEssential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
  • Tissue specificityUbiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers.
  • Sequence similaritiesBelongs to the mitofusin family.
  • Post-translational
    modifications
    Ubiquitinated by MARCH5.
  • Cellular localizationCytoplasm and Mitochondrion outer membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Fzo homolog antibody
    • Hfzo1 antibody
    • Hfzo2 antibody
    • MFN 1 antibody
    • Mfn1 antibody
    • MFN1_HUMAN antibody
    • Mitochondrial transmembrane GTPase Fzo 1 antibody
    • Mitochondrial transmembrane GTPase FZO 2 antibody
    • Mitochondrial transmembrane GTPase FZO1B antibody
    • Mitofusin 1 antibody
    • Mitofusin-1 antibody
    • Mitofusin1 antibody
    • MS996 antibody
    • Putative transmembrane GTPase antibody
    • Transmembrane GTPase MFN1 antibody
    see all

Anti-Mitofusin 1 antibody images

  • ab111271, at 3.75µg/ml, staining Mitofusin 1 in formalin-fixed, paraffin-embedded Human Adrenal tissue by Immunohistochemistry.
  • ab111271, at 3.75µg/ml, staining Mitofusin 1 in formalin-fixed, paraffin-embedded Human Uterus tissue by Immunohistochemistry.

References for Anti-Mitofusin 1 antibody (ab111271)

ab111271 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"