Anti-Mitofusin 1 antibody (ab123641)

Overview

  • Product nameAnti-Mitofusin 1 antibody
    See all Mitofusin 1 primary antibodies
  • Description
    Rabbit polyclonal to Mitofusin 1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 352-381 of Human Mitofusin 1 (NP_284941.2)

  • Positive control
    • Jurkat cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab123641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 84 kDa.

Target

  • FunctionEssential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
  • Tissue specificityUbiquitous. Expressed at slightly higher level in kidney and heart. Isoform 2 may be overexpressed in some tumors, such as lung cancers.
  • Sequence similaritiesBelongs to the mitofusin family.
  • Post-translational
    modifications
    Ubiquitinated by MARCH5.
  • Cellular localizationCytoplasm and Mitochondrion outer membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Fzo homolog antibody
    • Hfzo1 antibody
    • Hfzo2 antibody
    • MFN 1 antibody
    • Mfn1 antibody
    • MFN1_HUMAN antibody
    • Mitochondrial transmembrane GTPase Fzo 1 antibody
    • Mitochondrial transmembrane GTPase FZO 2 antibody
    • Mitochondrial transmembrane GTPase FZO1B antibody
    • Mitofusin 1 antibody
    • Mitofusin-1 antibody
    • Mitofusin1 antibody
    • MS996 antibody
    • Putative transmembrane GTPase antibody
    • Transmembrane GTPase MFN1 antibody
    see all

Anti-Mitofusin 1 antibody images

  • Anti-Mitofusin 1 antibody (ab123641) at 1/100 dilution + Jurkat cell line lysate at 35 µg

    Predicted band size : 84 kDa

References for Anti-Mitofusin 1 antibody (ab123641)

ab123641 has not yet been referenced specifically in any publications.

Product Wall

We have added the blocking peptide for ab123641 to the catalogue under the following name: Mitofusin 1 peptide (ab202006)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"