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ab56889 has been referenced in 63 publications.

  • Puschmann A  et al. Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism. Brain 140:98-117 (2017). WB ; Human . PubMed: 27807026
  • Tezze C  et al. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. Cell Metab 25:1374-1389.e6 (2017). PubMed: 28552492
  • Shinjo S  et al. Disruption of the mitochondria-associated ER membrane (MAM) plays a central role in palmitic acid-induced insulin resistance. Exp Cell Res 359:86-93 (2017). WB ; Human . PubMed: 28827061
  • Zhuang X  et al. Salidroside inhibits high-glucose induced proliferation of vascular smooth muscle cells via inhibiting mitochondrial fission and oxidative stress. Exp Ther Med 14:515-524 (2017). PubMed: 28672961
  • Vishnyakova PA  et al. Alterations in antioxidant system, mitochondrial biogenesis and autophagy in preeclamptic myometrium. BBA Clin 8:35-42 (2017). PubMed: 28736722
  • Benischke AS  et al. Activation of mitophagy leads to decline in Mfn2 and loss of mitochondrial mass in Fuchs endothelial corneal dystrophy. Sci Rep 7:6656 (2017). PubMed: 28751712
  • Kannan A  et al. Mitochondrial Reprogramming Regulates Breast Cancer Progression. Clin Cancer Res 22:3348-60 (2016). PubMed: 26888829
  • Stotland A & Gottlieb RA a-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J Mol Cell Cardiol 90:53-8 (2016). PubMed: 26654779
  • Jugé R  et al. Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes. Sci Rep 6:35065 (2016). PubMed: 27731355
  • Gao P  et al. Pro-apoptotic effects of rHSG on C6 glioma cells. Int J Mol Med 38:1190-8 (2016). PubMed: 27599901
  • Catalán-García M  et al. Mitochondrial DNA disturbances and deregulated expression of oxidative phosphorylation and mitochondrial fusion proteins in sporadic inclusion body myositis. Clin Sci (Lond) 130:1741-51 (2016). PubMed: 27413019
  • Agarwal S  et al. Dynamin-related Protein 1 Inhibition Mitigates Bisphenol A-mediated Alterations in Mitochondrial Dynamics and Neural Stem Cell Proliferation and Differentiation. J Biol Chem 291:15923-39 (2016). WB ; Rat . PubMed: 27252377
  • Malhotra A  et al. Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma. Mol Cancer Res 14:114-24 (2016). WB ; Mouse . PubMed: 26446920
  • Bal NC  et al. Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function. J Biol Chem 291:17247-57 (2016). PubMed: 27298322
  • Yu J  et al. Sevoflurane postconditioning attenuates cardiomyocyte hypoxia/reoxygenation injury via restoring mitochondrial morphology. PeerJ 4:e2659 (2016). Rat . PubMed: 27833818
  • Franco A  et al. Correcting mitochondrial fusion by manipulating mitofusin conformations. Nature 540:74-79 (2016). WB . PubMed: 27775718
  • Bruns DR  et al. Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction. Am J Physiol Lung Cell Mol Physiol 308:L158-67 (2015). PubMed: 25416385
  • Mourier A  et al. Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42 (2015). WB ; Mouse . PubMed: 25688136
  • Corsetti V  et al. NH2-truncated human tau induces deregulated mitophagy in neurons by aberrant recruitment of Parkin and UCHL-1: implications in Alzheimer's disease. Hum Mol Genet 24:3058-81 (2015). PubMed: 25687137
  • Wu SP  et al. Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure. Nat Commun 6:8245 (2015). PubMed: 26356605
  • Smolina N  et al. Primary Murine Myotubes as a Model for Investigating Muscular Dystrophy. Biomed Res Int 2015:594751 (2015). ICC . PubMed: 26380282
  • Song M  et al. Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblasts. Cell Metab 21:273-85 (2015). PubMed: 25600785
  • Bongers KS  et al. Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy. Am J Physiol Endocrinol Metab 308:E144-58 (2015). PubMed: 25406264
  • Wang C  et al. Dynamic tubulation of mitochondria drives mitochondrial network formation. Cell Res 25:1108-20 (2015). PubMed: 26206315
  • Xie Q  et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci 18:501-10 (2015). WB . PubMed: 25730670
  • Fiesel FC  et al. (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation. EMBO Rep 16:1114-30 (2015). PubMed: 26162776
  • Zhang J  et al. EglN2 associates with the NRF1-PGC1a complex and controls mitochondrial function in breast cancer. EMBO J 34:2953-70 (2015). PubMed: 26492917
  • Morén C  et al. Mitochondrial and apoptotic in vitro modelling of differential HIV-1 progression and antiretroviral toxicity. J Antimicrob Chemother 70:2330-6 (2015). PubMed: 25921514
  • Tabony AM  et al. Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function. Skelet Muscle 4:20 (2014). PubMed: 25625009
  • Fiesel FC  et al. A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci 127:3488-504 (2014). PubMed: 24928900
  • Fernandez-Sanz C  et al. Defective sarcoplasmic reticulum-mitochondria calcium exchange in aged mouse myocardium. Cell Death Dis 5:e1573 (2014). WB ; Mouse . PubMed: 25522267
  • Choubey V  et al. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy 10:1105-19 (2014). Rat . PubMed: 24879156
  • Cornelissen T  et al. The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy. Hum Mol Genet 23:5227-42 (2014). WB ; Mouse . PubMed: 24852371
  • Laafi J  et al. Pro-oxidant effect of ALA is implicated in mitochondrial dysfunction of HepG2 cells. Biochimie 106:157-66 (2014). PubMed: 25220386
  • Zhang J  et al. Comparative gene identification-58 (CGI-58) promotes autophagy as a putative lysophosphatidylglycerol acyltransferase. J Biol Chem 289:33044-53 (2014). PubMed: 25315780
  • Arruda AP  et al. Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity. Nat Med 20:1427-35 (2014). PubMed: 25419710
  • Chen HY  et al. Relationship between the expressions of mitofusin-2 and procollagen in uterosacral ligament fibroblasts of postmenopausal patients with pelvic organ prolapse. Eur J Obstet Gynecol Reprod Biol 174:141-5 (2014). Human . PubMed: 24361166
  • Koyano F  et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 510:162-6 (2014). PubMed: 24784582
  • Cornelius N  et al. Cellular consequences of oxidative stress in riboflavin responsive multiple acyl-CoA dehydrogenation deficiency patient fibroblasts. Hum Mol Genet N/A:N/A (2014). PubMed: 24698980
  • Vadnais ML  et al. Mitochondrial fusion protein MFN2 interacts with the mitostatin-related protein MNS1 required for mouse sperm flagellar structure and function. Cilia 3:5 (2014). WB ; Mouse . PubMed: 24876927
  • Bannwarth S  et al. A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement. Brain 137:2329-45 (2014). PubMed: 24934289
  • Yun J  et al. MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin. Elife (Cambridge) 3:e01958 (2014). WB ; Human . PubMed: 24898855
  • Cho B  et al. CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation. Exp Mol Med 46:e105 (2014). WB . PubMed: 25012575
  • Barbero-Camps E  et al. Endoplasmic reticulum stress mediates amyloid ß neurotoxicity via mitochondrial cholesterol trafficking. Am J Pathol 184:2066-81 (2014). Mouse . PubMed: 24815354
  • Zhang A  et al. Human cytomegalovirus inhibits apoptosis by proteasome-mediated degradation of Bax at endoplasmic reticulum-mitochondrion contacts. J Virol 87:5657-68 (2013). WB . PubMed: 23487455
  • Tasseva G  et al. Phosphatidylethanolamine deficiency in Mammalian mitochondria impairs oxidative phosphorylation and alters mitochondrial morphology. J Biol Chem 288:4158-73 (2013). WB . PubMed: 23250747
  • Miller MW  et al. Nitric oxide regulates vascular adaptive mitochondrial dynamics. Am J Physiol Heart Circ Physiol 304:H1624-33 (2013). Mouse, Rat . PubMed: 23585138
  • Mancini C  et al. Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. BMC Med Genomics 6:22 (2013). WB ; Human . PubMed: 23777634
  • Iguchi M  et al. Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J Biol Chem 288:22019-32 (2013). PubMed: 23754282
  • Chen Y  et al. Mitofusin 2 protects hepatocyte mitochondrial function from damage induced by GCDCA. PLoS One 8:e65455 (2013). WB ; Human . PubMed: 23755235
  • Salabei JK & Hill BG Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation. Redox Biol 1:542-51 (2013). WB ; Rat . PubMed: 24273737
  • Kim SJ  et al. Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis. PLoS Pathog 9:e1003722 (2013). Human . PubMed: 24339771
  • Koyano F  et al. The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons. Genes Cells 18:672-81 (2013). PubMed: 23751051
  • Tang G  et al. Mitochondrial abnormalities in temporal lobe of autistic brain. Neurobiol Dis 54:349-61 (2013). PubMed: 23333625
  • Sebastián D  et al. Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis. Proc Natl Acad Sci U S A 109:5523-8 (2012). WB, IHC-Fr ; Mouse . PubMed: 22427360
  • Chao LC  et al. Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res 53:2610-9 (2012). WB ; Mouse . PubMed: 23028113
  • Fyfe JC  et al. A novel mitofusin 2 mutation causes canine fetal-onset neuroaxonal dystrophy. Neurogenetics 12:223-32 (2011). WB ; Dog . PubMed: 21643798
  • Rakovic A  et al. Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts. PLoS One 6:e16746 (2011). WB ; Human . PubMed: 21408142
  • Zhang A  et al. Quantitative proteomic analyses of human cytomegalovirus-induced restructuring of endoplasmic reticulum-mitochondrial contacts at late times of infection. Mol Cell Proteomics 10:M111.009936 (2011). PubMed: 21742798
  • García-Pérez C  et al. Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points. Am J Physiol Heart Circ Physiol 301:H1907-15 (2011). PubMed: 21856920
  • Zhong Q & Kowluru RA Diabetic retinopathy and damage to mitochondrial structure and transport machinery. Invest Ophthalmol Vis Sci 52:8739-46 (2011). WB ; Rat . PubMed: 22003103
  • Hayashi T & Fujimoto M Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction. Mol Pharmacol 77:517-28 (2010). WB ; Chinese hamster . PubMed: 20053954
  • Onoguchi K  et al. Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1. PLoS Pathog 6:e1001012 (2010). WB ; Human . PubMed: 20661427

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