Overview

  • Product nameAnti-Mixl1 antibody
    See all Mixl1 primary antibodies
  • Description
    Mouse monoclonal to Mixl1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: QRRKRTSFSA EQLQLLELVF RRTRYPDIHL RERLAALTLL PESRIQVWFQ NRRAKSRRQS GKSFQPLARP EIILNHCAPG TETKCLKPQL PLEVDVNCLP , corresponding to amino acids 86-186 of Human Mixl1

Properties

Applications

Our Abpromise guarantee covers the use of ab57854 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionTranscription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression.
    • Tissue specificityRestricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B-and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level).
    • Sequence similaritiesBelongs to the paired homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • Post-translational
      modifications
      Phosphorylated at multiple sites.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • hMix antibody
      • Homeobox protein MIXL1 antibody
      • Homeodomain protein 1 antibody
      • Homeodomain protein MIX antibody
      • MILD1 antibody
      • MIX antibody
      • Mix.1 antibody
      • Mix.1 homeobox-like protein antibody
      • Mix1 homeobox-like 1 antibody
      • MIX1 homeobox-like protein 1 antibody
      • MIXL antibody
      • Mixl1 antibody
      • MIXL1_HUMAN antibody
      see all

    Anti-Mixl1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57854 Mixl1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-Mixl1 antibody (ab57854)

    This product has been referenced in:
    • Lee MR  et al. miR-124a is important for migratory cell fate transition during gastrulation of human embryonic stem cells. Stem Cells 28:1550-9 (2010). WB ; Human . Read more (PubMed: 20665740) »

    See 1 Publication for this product

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"