Overview

  • Product name
    ML-324
  • Description
    Potent, cell-permeable JMJD2 inhibitor
  • Biological description
    Potent, cell-permeable JMJD2 inhibitor (IC50 = 920 nM). Shows antiviral effects (IC50 = 10 μM), HSV-1 immediate early gene expression). Reversibly blocks human cytomegalovirus infection in vivo.

Properties

  • Chemical name
    N-[3-(Dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide
  • Molecular weight
    349.43
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C21H23N3O2
  • CAS Number
    1222800-79-4
  • PubChem identifier
    44143209
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in ethanol to 10 mM and in DMSO to 50 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    CN(C)CCCNC(=O)C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)O
  • Source

    Synthetic

  • Research areas

References

ab146175 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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