Recombinant
RabMAb

Anti-MLC1 antibody [EPR10942(2)] - N-terminal (ab186436)

Overview

  • Product name
    Anti-MLC1 antibody [EPR10942(2)] - N-terminal
    See all MLC1 primary antibodies
  • Description
    Rabbit Monoclonal [EPR10942(2)] to MLC1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human MLC1 aa 1-100 (N terminal). The exact sequence is proprietary.
    Database link: Q15049

  • Positive control
    • Human hypothalamus and hippocampus lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab186436 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 32 kDa (predicted molecular weight: 41 kDa).

Target

  • Function
    Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
  • Tissue specificity
    Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus.
  • Involvement in disease
    Leukoencephalopathy, megalencephalic, with subcortical cysts, 1
  • Cellular localization
    Membrane. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0027 antibody
    • LVM antibody
    • Megalencephalic leukoencephalopathy with subcortical cysts 1 antibody
    • Membrane protein MLC1 antibody
    • MLC antibody
    • MLC1 antibody
    • MLC1_HUMAN antibody
    • VL antibody
    • WKL1 antibody
    see all

Images

  • Anti-MLC1 antibody [EPR10942(2)] - N-terminal (ab186436) at 1/10000 dilution + Human hypothalamus lysate at 20 µg

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size: 41 kDa



    The observed MW is lower than the predicted 41kDa, which may be due to the high hydrophobicity of the protein.

  • Anti-MLC1 antibody [EPR10942(2)] - N-terminal (ab186436) at 1/1000 dilution + Human hippocampus lysate at 10 µg

    Secondary
    Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

    Predicted band size: 41 kDa



    The observed MW is lower than the predicted 41kDa, which may be due to the high hydrophobicity of the protein.

References

ab186436 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab186436.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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