Overview

  • Product name
    Anti-MLK2 antibody - N-terminal
    See all MLK2 primary antibodies
  • Description
    Rabbit polyclonal to MLK2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Mouse MLK2 aa 109-138 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q66L42

  • Positive control
    • K562 cell lysate; Mouse skeletal muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab172873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 104 kDa.

Target

  • Function
    Activates the JUN N-terminal pathway.
  • Tissue specificity
    Expressed in brain and skeletal muscle.
  • Sequence similarities
    Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.
  • Information by UniProt
  • Database links
  • Alternative names
    • M3K10_HUMAN antibody
    • MAP3K 10 antibody
    • Map3k10 antibody
    • MEKK10 antibody
    • Mitogen activated protein kinase kinase kinase 10 antibody
    • Mitogen-activated protein kinase kinase kinase 10 antibody
    • Mixed lineage kinase 2 antibody
    • MKN28 derived nonreceptor type serine/threonine kinase antibody
    • MKN28 kinase antibody
    • MLK 2 antibody
    • MST antibody
    • Protein kinase MST antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Mouse skeletal muscle tissue labeling MLK2 using ab172873 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-MLK2 antibody - N-terminal (ab172873) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size: 104 kDa

References

ab172873 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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