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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer Preservative: None
Constituents: 2% Sucrose, PBS
Concentration information loading...
Purity Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1.4 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 62 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Function Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.
Involvement in disease Note=A chromosomal aberration involving MLLT1 is associated with acute leukemias. Translocation t(11;19)(q23;p13.3) with MLL/HRX. The result is a rogue activator protein.
Sequence similarities Contains 1 YEATS domain.
Cellular localization Nucleus.
Information by UniProt
Anti-MLLT1 antibody images
Western blot - MLLT1 antibody (ab49052)
References for Anti-MLLT1 antibody (ab49052)
This product has been referenced in:
et al. Mutual Information Analysis Reveals Coevolving Residues in Tat That Compensate for Two Distinct Functions in HIV-1 Gene Expression. J Biol Chem 287:7945-55 (2012).
Read more (PubMed: 22253435) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"