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Rabbit polyclonal to MLLT1
This antibody recognizes MLLT1
Predicted to work with:
A region within synthetic peptide: SEDEASFKSE SAQSSPSNSS SSSDSSSDSD FEPSQNHSQG PLRSMVEDLQ, corresponding to internal sequence amino acids 361-410 of Human MLLT1
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1.4 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 62 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.
Involvement in disease
Note=A chromosomal aberration involving MLLT1 is associated with acute leukemias. Translocation t(11;19)(q23;p13.3) with MLL/HRX. The result is a rogue activator protein.
Contains 1 YEATS domain.
Information by UniProt
Western blot - Anti-MLLT1 antibody (ab49052)
Anti-MLLT1 antibody (ab49052) at 1.4 µg/ml + Raji cell lysate at 10 µg with 5% skimmed milk in PBS.
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size:
Observed band size:
58 kDa (
why is the actual band size different from the predicted?
Gel concentration: 12%
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