Overview

  • Product nameAnti-MLYCD antibody
    See all MLYCD primary antibodies
  • Description
    Mouse polyclonal to MLYCD
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human MLYCD protein (NP_036345.2).

  • Positive control
    • MLYCD transfected 293T lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab69675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 55 kDa.

Target

  • FunctionCatalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced. In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids.
  • PathwayMetabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from malonyl-CoA: step 1/1.
  • Involvement in diseaseMalonyl-CoA decarboxylase deficiency (MLYCD deficiency) [MIM:248360]: Autosomal recessive disease characterized by abdominal pain, chronic constipation, episodic vomiting, metabolic acidosis and malonic aciduria. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Cellular localizationMitochondrion. Cytoplasm. Peroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • DCMC_HUMAN antibody
    • hMCD antibody
    • Malonyl CoA decarboxylase antibody
    • Malonyl CoA decarboxylase mitochondrial antibody
    • Malonyl coenzyme A decarboxylase antibody
    • Malonyl-CoA decarboxylase antibody
    • MCD antibody
    • MGC59795 antibody
    • mitochondrial antibody
    • Mlycd antibody
    see all

References for Anti-MLYCD antibody (ab69675)

ab69675 has not yet been referenced specifically in any publications.

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