• Product nameAnti-MMP10 antibody
    See all MMP10 primary antibodies
  • Description
    Rabbit polyclonal to MMP10
  • SpecificityThis antibody is specific for MMP10, but does not cross react with the other MMP family members (MMP1, MMP2, MMP3, etc).
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Dog, Human
  • Immunogen

    Synthetic peptide based on the Hemopexin domain of the human MMP10.

    (Peptide available as ab41076.)

  • EpitopeThis antibody binds to the Hemopexin domain near the carboxyterminus.



Our Abpromise guarantee covers the use of ab28206 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: 1/1000 - 1/5000. Detects a band of approximately 56 kDa (pro-form, with a predicted molecular weight: 54 kDa) and a 46kDa band (inital active form), using reducing conditions. The final, hemopexin cleaved form is not detected. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCan degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.
    • Sequence similaritiesBelongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.
    • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • Cellular localizationSecreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • Matrix metallopeptidase 10 (stromelysin 2) antibody
      • Matrix metalloprotease 10 antibody
      • Matrix metalloproteinase 10 (stromelysin 2) antibody
      • Matrix metalloproteinase 10 antibody
      • Matrix metalloproteinase-10 antibody
      • MMP 10 antibody
      • MMP-10 antibody
      • Mmp10 antibody
      • MMP10_HUMAN antibody
      • SL 2 antibody
      • SL-2 antibody
      • SL2 antibody
      • STMY 2 antibody
      • STMY2 antibody
      • Stromelysin 2 antibody
      • Stromelysin II antibody
      • Stromelysin-2 antibody
      • Stromelysin2 antibody
      • StromelysinII antibody
      • Transin 2 antibody
      • Transin-2 antibody
      • Transin2 antibody
      see all

    Anti-MMP10 antibody images

    • All lanes : Anti-MMP10 antibody (ab28206) at 1/1000 dilution

      Lane 1 : MMP-10 at 0.1 µg
      Lane 2 : MMP-10 at 0.01 µg
      Lane 3 : MMP-10 at 0.001 µg
      Lane 4 : MMP-10 at 0.1 µg
      Lane 5 : MMP-10 at 0.01 µg
      Lane 6 : MMP-10 at 0.001 µg

      Predicted band size : 54 kDa
      Observed band size : 46,56 kDa (why is the actual band size different from the predicted?)

    References for Anti-MMP10 antibody (ab28206)

    This product has been referenced in:
    • Lee CW  et al. Nestin depletion induces melanoma matrix metalloproteinases and invasion. Lab Invest 94:1382-95 (2014). WB ; Mouse, Human . Read more (PubMed: 25365206) »
    • Doehn U  et al. RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells. Mol Cell 35:511-22 (2009). WB ; Human, Dog . Read more (PubMed: 19716794) »

    See all 2 Publications for this product

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